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Aging can lead to a reduction of all human capabilities. Loss of muscle or bone mass that causes sarcopenia, osteopenia, or osteoporosis with advancing age are major public health problems for the elderly population [ 56]. Bone loss has greatly affected elderly people. The bone-related medical treatments and costs are increasing in the aging population. Bone consists of a mineral phase (calcium phosphate) and an organic phase (collagen). The challenge in bone tissue engineering is to develop scaffolds having good biological and biomechanical properties [ 57]. Scaffolds can promote bone formation by differentiating towards the osteogenic lineage or releasing specific soluble molecules [ 58]. Scaffold architecture is very important for bone regeneration and acellular materials should allow proper host cell colonization for bone regeneration. In addition, mean pore size is another key component for proper cell colonization. Collagen-glycosaminoglycan scaffolds showed a substantial improvement in pore size [ 59]. Choi FD. Sung CT, Juhasz MLW, Mesinkovska NA. Oral collagen supplementation: A systematic review of dermatological applications. J Drugs Dermatol. 2019;18(1):9-16. PMID:30681787. I ) , α 2 ( I ) , α 1 ( II ) , α 1 ( III ) , α 1 ( IV ) , α 2 ( IV ) , α 3 ( IV ) , α 4 ( IV ) , α 5 ( IV ) , α 6 ( IV ) , α 1 ( V ) , α 2 ( V ) , and α 3 ( V ) are proteins encoded by COL1A1, COL1A2, COL2A1, COL3A1, COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6, COL5A1, COL5A2 and COL5A3 genes, respectively. Our Marine Collagen’s enhanced formulation is blended with hydrating Hyaluronic Acid. Additionally it contains Vitamin C, which contributes to normal collagen formation for normal function of the skin, Vitamin E which contributes to the protection of cells.
Bagheri Miyab K, Alipoor E, Vaghardoost R, Saberi Isfeedvajani M, Yaseri M, Djafarian K, Hosseinzadeh-Attar MJ. The effect of a hydrolyzed collagen-based supplement on wound healing in patients with burn: A randomized double-blind pilot clinical trial. Burns. 2020 Feb;46(1):156-163. doi: 10.1016/j.burns.2019.02.015. Epub 2019 Dec 16. PMID: 31859087. Our Hydrolysed Marine Collagen is derived from wild fish such as Cod (Gadidae) that are sourced in an environmentally-friendly and sustainable way from various regions across the world (EU, South America, Southeast Asia). Our hydrolysed collagen has NO artificial colours and flavours; and NO excipients, binders or fillers -- only pure and active ingredients. Yang FC, Zhang Y, Rheinstädter MC. The structure of people's hair. PeerJ. 2014;2:e619. doi:10.7717/peerj.619
Kiki Health Pure Marine Collagen Powder
However, these types of collagen products can provide a source that is more transparent to ensure only safe animals are used in production. It can remove concerns about water pollutions that infect sea life getting into the product.
Read more: Shop The Best Beauty Advent Calendars 2023 Has To Offer Which collagen is best type 1, 2 or 3? Perhaps best known for its benefits to your skin and overall beauty, collagen, derived from the Greek word for glue, "Kólla", is the most abundant protein in our bodies. It plays a vital role in strengthening connective tissues and holding everything together. Found primarily in the skin, bones, tendons, and other connective tissues, collagen is essential for maintaining their health and integrity. However, as we age, our ability to produce collagen decreases, which contributes to the development of wrinkles and other signs of aging. Why choose Healthspan's Marine Collagen? Another main problem with marine collagen is its source. It can be difficult to know precisely where and with what the marine collagen was created. If the marine life was sourced from an area that is high in toxins, those toxins could be in the supplement. One toxin, BMAA, that is linked to ALS, is not tested before the product is marketed. No matter the source, all types of collagen target the effects of ageing. As a general rule, Logan suggests opting for a well-researched hydrolysed, marine-sourced, Type 1 collagen. “Type 1 collagen provides the main support for the skin, helping to provide structure,” she says. “ As it breaks down, we start to lose that structure, which can lead to the signs of ageing. Research has indicated that keeping collagen levels high in the body, by using absorbable collagen peptides, can help to slow the down the development of lines and wrinkles.” How do I choose a collagen supplement? de Miranda RB, Weimer P, Rossi RC. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Int J Dermatol. 2021;60(12):1449-1461. doi:10.1111/ijd.15518Porcine collagen is another type of collagen developed mostly from pigs. This type of collagen has shown increased benefits in aiding hair and skin. Again, the type of collagen a person chooses will often depend on their personal needs and beliefs. Which Fish ? Pangasius fish. This is one of the best fish if not the best for collagen. How do we know ? The Amino Acid profile. There are types of collagen supplements that are not hydrolyzed. These are often made directly from the gelatin product created when sourcing collagen from the various animals used for the product. This gelatin can be easily transformed into tablets, powders, or other products for easy consumption.
Supplementing with marine collagen may lead to faster and more complete healing of wounds. As the main component of the dermal matrix of the skin, collagen is necessary for regeneration of skin after any skin injury or deformation, such as scars, rashes, and burns. Supplementing with marine collagen peptides may be an important component of wound healing by helping to promote cell proliferation, protein synthesis, and regenerating the extracellular matrix for tissue strength. 6. MAY REDUCE INFLAMMATION Bioactive peptides from marine sources, including hydrolyzed marine collagen, have antioxidant properties that can reduce the presence of reactive oxygen species throughout the body. 9 Reactive oxygen species cause aging of tissues, higher risk of cancer, and inflammatory responses throughout the body. Antioxidants are an important protection against accumulation of reactive oxygen species and also help to boost the immune system. Studies have shown decreased levels of reactive oxygen species after treatment with marine collagen peptides, showing that supplementing with marine collagen may help to reduce inflammation. 7. ANTIBACTERIAL EFFECTS Recent research has discovered that peptide fragments contained within marine collagen have antibacterial properties. Specifically, collagencin, a peptide derived from collagen, has been found to inhibit the growth of infection and disease causing bacteria. A 2016 study showed collagencin completely inhibits the growth of the common bacterium Staphylococcus Locus, commonly known as staph infection, and partially inhibits the activity of other bacteria, including E. Coli. 10 The authors in the study concluded that marine collagens are a promising source of antimicrobial agents with positive implications on human health. While the research is still ongoing, the ability to inhibit the growth of staph infection and E. coli through supplementation with marine collagen peptides could be a great alternative to antibiotics. 8. SUPERIOR MEANS OF WEIGHT MANAGEMENT Marine collagen does not contain any carbs, sugar or fat. Daily intake of marine collagen may help to suppress appetite by keeping you feeling full longer and thus can help promote weight loss. Is Marine Collagen the Right Option for You?Collagen can be sourced from land animals as well. There are various types that can come from beef or pork to provide the same benefits as marine collagen can provide. Unfortunately, many people who have concerns with the beef or pork industries may have reservations about using these products. Typically speaking, collagen supplements take a minimum of three months to work, which is approximately two complete skin cycles. “This ensures the new cells coming up to the surface are of the highest quality, please note, in some cases this will take longer as the body uses collagen in many other areas, not just the skin,” says Ghatora. When should I take collagen, in the morning or at night? Wondering what exactly marine collagen is? Perhaps you know what it is, but you're not sure what it can do for you. In other words, what are the health benefits of hydrolyzed marine collagen peptides? Marine collagen, which comes exclusively from fish, has numerous health benefits, especially beauty benefits. These include helping to reduce the appearance of wrinkles and scars, possibly helping in stabilizing blood sugar, reducing inflammation, and so much more. Marine collagen is easily absorbed and highly effective. It's here to help you fight aging from the inside out. It's also great for pescetarians too! Here we provide everything you need to know about what is marine collagen: where it comes from and 8 amazing marine collagen benefits. What is Marine Collagen? Collagen is the most abundant protein in our body, yet our bodies produce less and less of it with each passing year. Since most of us don’t get enough collagen through our diets, supplementing with a quality source of collagen peptides is essential to keeping our bodies strong and healthy. This is where Marine Collagen Peptides can help. There are lots of marine collagen peptides benefits. Collagen peptides can come from different sources, including bovine and other animals. Marine Collagen Peptides are derived entirely from fish collagen, either fish skin or scales. The unique composition and structure of Marine Collagen Peptides provide numerous health benefits as explained below. 1. Marine collagen is highly bioavailable One marine collagen benefit is that it has superior absorption and bioavailability. Marine collagen has the smallest particle size and lowest molecular weight among all collagen types, which allows it to pass through the intestinal wall into the bloodstream more easily to provide better healing, repair, and nourishment. Marine collagen is absorbed up to 1.5 times more efficiently than other types of collagen, making it one of the best and effective types of collagen. 2. Type 1 Collagen Another marine collagen peptides benefit is that it is predominantly made up of Type 1 Collagen. There are over forty different types of collagen throughout the body that vary in their composition and function, but Type 1 collagen is the most abundant collagen in our body. Marine collagen consists almost entirely of Type 1 collagen, which is an important component of skin, bone, teeth, muscles, tendons, ligaments, and fascia. Some Marine Collagens, like Further Food Premium Marine Collagen, also contain Types 2 and 3 collagen, which can provide skin and joint benefits. 3. Rich in the amino acids glycine and proline An important marine collagen benefit is that it provides 8 out of 9 essential amino acids, including substantial amounts of glycine and proline which perform important functions throughout the body. Glycine is an all-encompassing amino acid that promotes the building of lean muscle mass, impacts the central nervous system to prevent the formation of stomach ulcers, has anti-inflammatory and antioxidant properties, and improves glucose tolerance to protect against diabetes. Proline is important for stimulating collagen synthesis and works as an antioxidant by scavenging free radicals to prevent cell damage. 4. It's environmentally friendly A marine collagen benefit that you might not know is that marine collagen is the most environmentally sustainable source of collagen. An estimated 60% of by-products of fish processing become waste 1 , but researchers recently discovered that these by-products, especially the collagen-rich fish skin, have amazing health-boosting properties. Additionally, marine collagen made from fish skin helps to reduce environmental pollution, and provides a superior and beneficial source of collagen protein. . Marine Collagen Benefits For Health and Beauty As we age, our body’s ability to produce new collagen declines, and existing collagen begins to break down. This loss of collagen is the root of aging of our skin, joints and bones, and this diminished supply can lead to increased digestive problems, a weakened immune system, and increased risk of chronic illness. Fortunately, science has shown that collagen supplementation may protect against and reverse these effects. There are lots of benefits of marine collagen powder. Here are 8 benefits of marine collagen supplements: 1. BUILDS BONE STRENGTH The loss of bone mass is one of the most common signs of aging and can lead to osteoporosis, which affects over 75 million people throughout the U.S., Europe, and Japan. Making sure we have enough calcium and phosphorus is essential to maintaining bone strength. However, these minerals are difficult to absorb, resulting in deficiencies and putting us at risk for bone loss and bone disease. Studies have shown that marine collagen peptides may help the absorption of calcium and other minerals that are essential for bone strength 2 . Additionally, marine collagen supplementation may stimulate collagen synthesis in the bones by promoting bone-building cells, called osteoblasts, 3 that build the organic matrix of bone, which is 90% collagen. 2. MAY HELP SLOW AGING The collagen in our skin begins breaking down at age 21 and continues to be degraded throughout adulthood, leading to saggy, wrinkly skin as we get older. 70% of our skin is made of Type 1 collagen, and supplementing with Marine Peptides, which are a Type 1 collagen, may help to replenish our skin and may even help to reverse aging. Clinical trials have shown patients who supplement with marine collagen have a decrease in wrinkles and improved skin hydration and firmness. 4,5 3. HIGH LEVELS OF GLYCINE WHICH HELPS SUPPORT BLOOD SUGAR LEVELS Marine collagen has a unique amino acid composition with higher glycine levels than any other types of collagen. Scientists are continuing to discover the beneficial roles of glycine throughout the body, specifically in relation to supporting healthy blood sugar levels. Recent research has found a connection between low blood glycine levels and impaired glucose tolerance, which suggests low glycine may lead to insulin resistance and ultimately diabetes. In fact, a 2016 study by the Alberta Diabetes Institute found consistently low levels of circulating glycine among people with type 2 diabetes. 6 4. MAY HELP LOWER CHOLESTEROL LEVELS Marine collagen supplementation has been shown in clinical trials to lower LDL (the bad lipoprotein) and increase HDL (the good lipoprotein) 7 . HDL is the “good” lipoprotein that pulls cholesterol and triglycerides out of the blood and tissues to help prevent tissue damage caused by fats. It is believed that marine collagen peptides may help promote genetic factors that regulate lipid metabolism and control cholesterol levels. 5. MAY HELP IMPROVE WOUND HEALING & REDUCES SCARS
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